Discussion
Diagnosis With Brief Discussion
- Diagnosis
- SLE pleuritis/pleurisy
- Radiologic Findings
- Fig 1. Chest PA shows left pleural effusion.
Fig 2-7. Chest CT scans reveal subtle high density bilateral pleural effusion with pleural thickening and pericardial effusion. There are focal enhancing dot-like lesions in pleural effusion and pericardial effusion
Fig 8. [3 years ago] Chest CT scan shows bilateral pleural effusion and a small amount of pericardial effusion with mild pericardial thickening.
- Brief Review
- Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by inflammation, immune complex deposition, vasculitis, and vasculopathy. Involvement of the respiratory system in SLE is relatively common. SLE can affect the pleura, lung, and respiratory muscles, all contributing to respiratory dysfunction.
Pleural effusions are the most common manifestation of SLE in the respiratory system and are bilateral in approximately 50% of patients. Pleural effusions in SLE are generally small and are exudative, containing lupus erythematosus cells, immune complexes, and anti-DNA antibodies, among other things. Pleuritis and pleural fibrosis are reported in 50%
- References
- 1. Tasneem A. Lalani, Jeffrey P. Kanne, Gregory A. Hatfield, Phebe Chen. Imaging Findings in Systemic Lupus Erythematosus. RadioGraphics 2004; 24:1069-1086.
2. Kim JS, Lee KS, Koh E, Kim SY, Chung MP, Han J. Thoracic Involvement of Systemic Lupus Erythematosus: Clinical, Pathologic, and Radiologic Findings. J Comput Assist Tomogr.2000 Jan-Feb;24(1):9
- Keywords
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